Early or Delayed Cardioversion in Recent-Onset Atrial Fibrillation (Record no. 12943)

MARC details
000 -CABECERA
campo de control de longitud fija 03442nab a2200289 4500
003 - NÚMERO DE CONTROL
campo de control CO-MdCUR
005 - FECHA Y HORA DE ACTUALIZACIÓN
005 20190726110638.0
007 - CAMPO FIJO DE DESCRIPCIÓN FÍSICA--INFORMACIÓN GENERAL
campo de control de longitud fija ta
008 - LONGITUD FIJA
campo de control de longitud fija 170814s2019 xxu||||| |||| 00| 0 eng d
040 ## - FUENTE DE CATALOGACIÓN
Centro/agencia transcriptor Remington
Centro catalogador/agencia de origen CO-MdCUR
Normas de descripción rda
041 ## - IDIOMA
Código de idioma Inglés
082 ## - CLASIFICACIÓN DECIMAL DEWEY
edición 21
773 0# - ENLACE AL DOCUMENTO FUENTE
Número bibliográfico anfitrión 11137
Número de ítem anfitrión 23482
Encabezamiento principal Massachusetts Medical Society
Lugar, editor y fecha de publicación Boston, Massachusetts Medical Society.
Otro identificador del documento 19654
Título The New England journal of medicine.
Número de control del registro 11137412
Número Internacional Normalizado para Publicaciones Seriadas 0028-4793
100 1# - AUTOR PERSONAL
9 (RLIN) 39358
nombre Pluymaekers, Nikki A.H.A.
245 1# - TÍTULO PROPIAMENTE DICHO
título Early or Delayed Cardioversion in Recent-Onset Atrial Fibrillation
264 ## - PIE DE IMPRENTA
lugar (ciudad) Boston :
editorial Massachusetts Medical Society ,
fecha 2019
300 ## - DESCRIPCIÓN FÍSICA
Extensión páginas 1499 - 1508
520 3# - RESUMEN
Resumen BACKGROUND<br/>Patients with recent-onset atrial fibrillation commonly undergo immediate restoration of sinus rhythm by pharmacologic or electrical cardioversion. However, whether immediate restoration of sinus rhythm is necessary is not known, since atrial fibrillation often terminates spontaneously.<br/><br/>METHODS<br/>In a multicenter, randomized, open-label, noninferiority trial, we randomly assigned patients with hemodynamically stable, recent-onset (<36 hours), symptomatic atrial fibrillation in the emergency department to be treated with a wait-and-see approach (delayed-cardioversion group) or early cardioversion. The wait-and-see approach involved initial treatment with rate-control medication only and delayed cardioversion if the atrial fibrillation did not resolve within 48 hours. The primary end point was the presence of sinus rhythm at 4 weeks. Noninferiority would be shown if the lower limit of the 95% confidence interval for the between-group difference in the primary end point in percentage points was more than −10.<br/><br/>RESULTS<br/>The presence of sinus rhythm at 4 weeks occurred in 193 of 212 patients (91%) in the delayed-cardioversion group and in 202 of 215 (94%) in the early-cardioversion group (between-group difference, −2.9 percentage points; 95% confidence interval [CI], −8.2 to 2.2; P=0.005 for noninferiority). In the delayed-cardioversion group, conversion to sinus rhythm within 48 hours occurred spontaneously in 150 of 218 patients (69%) and after delayed cardioversion in 61 patients (28%). In the early-cardioversion group, conversion to sinus rhythm occurred spontaneously before the initiation of cardioversion in 36 of 219 patients (16%) and after cardioversion in 171 patients (78%). Among the patients who completed remote monitoring during 4 weeks of follow-up, a recurrence of atrial fibrillation occurred in 49 of 164 patients (30%) in the delayed-cardioversion group and in 50 of 171 (29%) in the early-cardioversion group. Within 4 weeks after randomization, cardiovascular complications occurred in 10 patients and 8 patients, respectively.<br/><br/>CONCLUSIONS<br/>In patients presenting to the emergency department with recent-onset, symptomatic atrial fibrillation, a wait-and-see approach was noninferior to early cardioversion in achieving a return to sinus rhythm at 4 weeks. (Funded by the Netherlands Organization for Health Research and Development and others; RACE 7 ACWAS ClinicalTrials.gov number, NCT02248753.)
650 #0 - MATERIA GENERAL
9 (RLIN) 8005
Término de materia o nombre geográfico como elemento inicial Fibrilación auricular
700 1# - COAUTOR PERSONAL
9 (RLIN) 39359
Nombre de persona Dudink, Elton A. M. P.
700 1# - COAUTOR PERSONAL
9 (RLIN) 39360
Nombre de persona Luermans, Justin G. L. M.
942 ## - PUNTO DE ACCESO ADICIONAL KOHA
Fuente del sistema de clasificación o colocación Dewey Decimal Classification
Tipo de ítem Koha Hemeroteca

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